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proteomic Data Base

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Cancer proteome databases encompass tumor tissues, cells, and biological fluids to interpret signaling pathways, identifying signatures related to tumor initiation, invasion and metastasis, and the discovery of analytical, predictive, and prognostic markers(Arntzen, Boddie et al. 2015), and also Determining the molecular details of proteome differentiation in various human tissues and organs and greatly improve our understanding of disease and human biology(Uhl??n, Fagerberg et al. 2015). A number of databases have been published in this research area such as "CanProVar" is designed to store and display single amino acid alterations including both germline and somatic variations in the human proteome, particularly those related to the genesis or development of human cancer based on the published literatures and sources(Li, Duncan et al. 2010).