iCSDB is an integrated database of CRISPR-CAS9 screening experiments for human cell lines. We compiled two major sources of CRISPR-CAS9 screening - DepMap portal and BioGRID ORCS. DepMap portal itself is an integrated database to include three large-scale projects of CRISPR screening (DepMap, Sanger, and GeCKO). Additionally, we aggregated CRISPR-CAS9 screens from BioGRID ORCS that collected CRISPR screening results from PubMed articles. Clinical and molecular information was integrated to help users select cell lines of interest readily.