At its core, DAnCER collates records of CM-related genes from human and several model organisms, which were curated from literature and from other experimentally-annotations genomic databases (so-called 'confirmed' CM genes). This collection is then significantly expanded with hundreds of additional genes ('putative' CM genes), whose CM function has not yet been experimentally validated, but was predicted by our team based on their similarity in sequence and protein-domain composition to 'confirmed' CM genes. For all genes and proteins, DAnCER also displays information on homology relationships, domain architecture, membership in protein complexes, comparison to known protein 3D structures (a fuzzy-match scan performed over the entire Protein Data Bank), classification of 3D structures into SCOP families, and other supporting evidence.