Cell death especially Programmed cell-death (or PCD) is critical for development and health of multicellular organisms. Previously, apoptosis is identified to be the primary mechanism while cells are eliminated physiologically in metazoan organisms or plants (Kerr et al., 1972). Recently, in contrast to traditionally consideration as a simple way to die, necrosis has emerged as an alternate form of programmed cell death (Proskuryakov et al., 2003).