Pathway diagrams are the roadmaps for molecular biology, which illustrate the connections between genes, proteins and metabolites(Wishart, Li et al. 2020).Well-illustrated pathway database provides biological context to complex molecular processes in an easily understood and highly visual manner. In this regard, pathway databases provide a remarkably useful information for scientists to share, integrate, interpret and visualize omics data and omics measurements(Wishart, Li et al. 2020).for more details, we have collected the updated 40 Protein Pathway databases for easy search.